Maintenance of DNMT1-Mediated DNA Methylation Patterns

Stearoyl-CoA Desaturase 1 Exercise Determines the Upkeep of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells

Metabolic stress, comparable to lipotoxicity, impacts the DNA methylation profile in pancreatic β-cells and thus contributes to β-cell failure and the event of kind 2 diabetes (T2D).

Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiting enzyme that is involved in monounsaturated fatty acid synthesis, which protects pancreatic β-cells in the direction of lipotoxicity. The present analysis found that SCD1 can be required for the establishment and maintenance of DNA methylation patterns in β-cells.

• We confirmed that SCD1 inhibition/deficiency prompted DNA hypomethylation and adjusted the methyl group distribution inside chromosomes in β-cells. Lower ranges of DNA methylation in SCD1-deficient β-cells have been adopted by lower ranges of DNA methyltransferase 1 (DNMT1).

• We moreover found that the downregulation of SCD1 in pancreatic β-cells led to the activation of adenosine monophosphate-activated protein kinase (AMPK) and an increase inside the train of the NAD-dependent deacetylase sirtuin-1 (SIRT1).
• Furthermore, the bodily affiliation between DNMT1 and SIRT1 stimulated the deacetylation of DNMT1 beneath circumstances of SCD1 inhibition/downregulation, suggesting a mechanism by which SCD1 exerts administration over DNMT1.

• We moreover found that SCD1-deficient β-cells which were dealt with with compound c, an inhibitor of AMPK, have been characterised by bigger ranges of every worldwide DNA methylation and DNMT1 protein expression in distinction with untreated cells.

• Subsequently, we found that activation of the AMPK/SIRT1 signaling pathway mediates the affect of SCD1 inhibition/deficiency on DNA methylation standing in pancreatic β-cel
• Altogether, these findings suggest that SCD1 is a gatekeeper that protects β-cells in the direction of the lipid-derived lack of DNA methylation and provide mechanistic insights into the mechanism by which SCD1 regulates DNA methylation patterns in β-cells and T2D-relevant tissues.

Pneumocystis carinii antibody
10R-2449	Fitzgerald	100 ug	EUR 469.2
Description: Mouse monoclonal Pneumocystis carinii antibody

Pneumocystis Carinii Antibody
abx022157-100ug	Abbexa	100 ug	EUR 886.8

Pneumocystis Carinii Antibody
abx022158-100ug	Abbexa	100 ug	EUR 886.8

Pneumocystis jiroveci PCR kit
PCR-H440-48D	Bioingentech	50T	EUR 543.6

Pneumocystis jiroveci PCR kit
PCR-H440-96D	Bioingentech	100T	EUR 686.4

Anti-Human Pneumocystis Carinii antibody
STJ16100417	St John's Laboratory	1 mL	EUR 896.4

0.2ML CLEAR STRIP CAPS FOR REAL TIME PCR
PCR-2CP-RT-C	CORNING	125/pk	EUR 267.6
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

Monkeypox Virus Real Time PCR Kit
PDPS-AR064	Creative Biogene	1 unit	Ask for price
Description: Creative Biogene Monkeypox Virus Real Time PCR Kit is used for the detection of monkeypox Virus in serum or lesion exudate samples by using real time PCR systems. Monkeypox virus (MPV) is a double-stranded DNA, zoonotic virus and a species of the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. The kit contains a specific ready-to-use system for the detection of the monkeypox Virus. Fluorescence is emitted and measured by the real time systems' optical unit during the PCR.

Monkeypox Virus Real Time PCR Kit
YJC70115NW-25T	Jiangsu Bioperfectus Technologies	25 tests/kit	Ask for price
Description: The Bioperfectus Monkeypox Virus Real Time PCR Kit is an in vitro diagnostic test, based on real-time PCR technology, for the detection of DNA from the Monkeypox virus. Specimens can be obtained from human serum, lesion exudate samples and scab. BSL-2 facilities with standard BSL-2 work practices may be used for the test of t he Monkeypox virus.

Monkeypox Virus Real Time PCR Kit
ZD-0076-01	Gentaur Genprice	25 tests/kit	Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids. The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long. The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of the Monkeypox Virus DNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channel 530nm with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the 560nm fluorescence of the internal control (IC). An external positive control defined as 1×10^7 copies/ml is supplied which allow the determination of the gene load.

Monkeypox Virus Real Time PCR Kit
ZD-0076-02	Gentaur Genprice	25 tests/kit	Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids.The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long.The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of theMonkeypox VirusDNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channelFAM with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the HEX/VIC/JOE fluorescence of the internal control (IC). An external positive control defined as 1×107copies/ml is supplied which allow the determination of the gene load.

lyophilised real-time PCR Master Mix for dual labeled probes
M-PCR-156L	MiTeGen	960 reactions x 20 µl	EUR 900.68
Description: lyophilised real-time PCR Master Mix for dual labeled probes

lyophilised real-time PCR Master Mix for dual labeled probes
M-PCR-156S	MiTeGen	192 reactions x 20 µl	EUR 225.3
Description: lyophilised real-time PCR Master Mix for dual labeled probes

TurboQ Real-time PCR Machine with Laptop
MOL2700	Scientific Laboratory Supplies	EACH	EUR 30805.08

lyophilised real-time PCR Master Mix with SYBR® Green fluorescent DNA stain
M-PCR-173L	MiTeGen	960 reactions x 20 µl	EUR 789.36
Description: lyophilised real-time PCR Master Mix with SYBR® Green fluorescent DNA stain

lyophilised real-time PCR Master Mix with SYBR® Green fluorescent DNA stain
M-PCR-173S	MiTeGen	192 reactions x 20 µl	EUR 197.34
Description: lyophilised real-time PCR Master Mix with SYBR® Green fluorescent DNA stain

hsa-mir-521 Real-time RT-PCR Detection Kit
20-abx097600	Abbexa	EUR 661.20 EUR 944.40 EUR 477.60	100 rxns 200 rxns 50 rxns

dsGreen for Real-Time PCR, 100×, 2 mL
61010	Lumiprobe	2 mL	EUR 435.6

dsGreen for Real-Time PCR, 100×, 1 mL
41010	Lumiprobe	1 mL	EUR 298.8

dsGreen for Real-Time PCR, 100×, 10 mL
81010	Lumiprobe	10 mL	EUR 1042.8

dsGreen for Real-Time PCR, 100×, 5 mL
71010	Lumiprobe	5 mL	EUR 750

Pneumocystis jiroveci RT PCR kit
RTq-H440-100D	Bioingentech	100T	EUR 860.4

Pneumocystis jiroveci RT PCR kit
RTq-H440-150D	Bioingentech	150T	EUR 969.6

Pneumocystis jiroveci RT PCR kit
RTq-H440-50D	Bioingentech	50T	EUR 717.6

PMA Real-Time PCR Bacterial Viability Kit - Staphylococcus aureus (mecA)
31036	Biotium	1kit	EUR 478.8
Description: Minimum order quantity: 1 unit of 1kit

PMA Real-Time PCR Bacterial Viability Kit - E. coli (uidA)
31050	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

PMA Real-Time PCR Bacterial Viability Kit - Listeria monocytogenes (hly)
31051	Biotium	1kit	EUR 478.8
Description: Minimum order quantity: 1 unit of 1kit

PMA Real-Time PCR Bacterial Viability Kit - Legionella pneumophila (mip)
31053	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

ReadiView® Blue Real-Time PCR Visualization Dye *200X*
17300	AAT Bioquest	500 Tests	EUR 97

Pneumocystis jiroveci One-Step PCR kit
Oneq-H440-100D	Bioingentech	100T	EUR 1039.2

Pneumocystis jiroveci One-Step PCR kit
Oneq-H440-150D	Bioingentech	150T	EUR 1177.2

Pneumocystis jiroveci One-Step PCR kit
Oneq-H440-50D	Bioingentech	50T	EUR 861.6

qPCR MultiplexMasterMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-321L	MiTeGen	10 x 1,25 ml	EUR 1438.81
Description: qPCR MultiplexMasterMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

qPCR MultiplexMasterMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-321S	MiTeGen	2 x 1,25 ml	EUR 359.77
Description: qPCR MultiplexMasterMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

PMA Real-Time PCR Bacterial Viability Kit - Salmonella enterica (invA) PMAxx
31033-X	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

PMA Real-Time PCR Bacterial Viability Kit - E. coli (uidA) PMAxx
31050-X	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

PMA Real-Time PCR Bacterial Viability Kit - Listeria monocytogenes (hly) PMAxx
31051-X	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit
RR-0478-02	Liferiver	25 tests/kit	EUR 1189.2
Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems.

Axygen Polyester ultra clear sealing film for real time PCR
AXY2152	Scientific Laboratory Supplies	PK100	EUR 336.3

qPCR MultiplexMaster lowROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-322L	MiTeGen	10 x 1,25 ml	EUR 1438.81
Description: qPCR MultiplexMaster lowROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

qPCR MultiplexMaster lowROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-322S	MiTeGen	2 x 1,25 ml	EUR 359.77
Description: qPCR MultiplexMaster lowROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

qPCR MultiplexMaster highROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-323L	MiTeGen	10 x 1,25 ml	EUR 1438.81
Description: qPCR MultiplexMaster highROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

qPCR MultiplexMaster highROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service
M-PCR-323S	MiTeGen	2 x 1,25 ml	EUR 359.77
Description: qPCR MultiplexMaster highROXMaster mix for multiplex real-time PCR** shipped ice packs - must be shipped via overnight service

Human Schwann Cell PCR Primer Library
HSCH-I	Real Time Primers	1 set	EUR 657.6

Human Lung Cancer PCR Primer Library
HLUCPL-I	Real Time Primers	1 set	EUR 657.6

PMA Real-Time PCR Bacterial Viability Kit - E. coli O157:H7 (Z3276)
31037	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

hsa-mir-521 Real-Time RT-PCR Detection and U6 Calibration Kit
20-abx097601	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

Human Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit
DD2H	Detroit R&D	1 Kit	EUR 516

Mouse Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit
DD2M	Detroit R&D	1 Kit	EUR 516

Rat Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit
DD2R	Detroit R&D	1 Kit	EUR 516

PCR Mycoplasma Detection Kit
M034-Kit	TOKU-E	Kit	EUR 319.2

qPCR plate-foil universal (for Real-time PCR, Light Cycler 480)
A26979	GeneOn	1x100 pcs	EUR 223.2

Eco 48 Real Time PCR system including software and loading dock
MOL6348	Scientific Laboratory Supplies	EACH	EUR 19520.22

Eztime Real - time PCRPremix 2x,Taqman
FYT105-100P	Yeastern Biotech	100 Preps 1.25 ml	Ask for price

PMA Real-Time PCR Bacterial Viability Kit - E. coli O157:H7 (Z3276) PMAxx
31037-X	Biotium	1kit	EUR 513.6
Description: Minimum order quantity: 1 unit of 1kit

SYBR® Green Fluorescent DNA StainDNA intercalation dye for real-time PCR analysis** shipped ice packs - must be shipped via overnight service
M-PCR-378	MiTeGen	500 µl	EUR 63.63
Description: SYBR® Green Fluorescent DNA StainDNA intercalation dye for real-time PCR analysis** shipped ice packs - must be shipped via overnight service

Pneumocystis Stain Kit
PCS-1	ScyTek Laboratories	1 kit(s)	EUR 187.2

Pneumocystis Stain Kit
PCS-2	ScyTek Laboratories	100 Slides	EUR 124.8

Pneumocystis Stain Kit
K1434-125	Biovision	each	EUR 510

Pneumocystis Stain Kit
K1434-30	Biovision	each	EUR 379.2

0,1ML THIN WALL TUBES 8 PER STRIP. CLEAR & REAL TIME STRIP CAPS
PCR-0108-LP-RT-C	CORNING	125/pk	EUR 850.8
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

0,1ML THIN WALL TUBES 8 PER STRIP. WHITE & REAL TIME STRIP CAPS
PCR-0108-LP-RT-W	CORNING	125/pk	EUR 924
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

Eztime Real - time PCRPremix 2x,SYBR Green
FYT103-100P	Yeastern Biotech	100 Preps 1.25 ml	Ask for price

Eztime Real - time PCRPremix 2x,SYBR Green
FYT103-400P	Yeastern Biotech	400 Preps 1.25 ml x 4	Ask for price

Eztime Real - time PCRPremix 2x,SYBRGreen , ROX
FYT104-100P	Yeastern Biotech	100 Preps 1.25 ml	Ask for price

Eztime Real - time PCRPremix 2x,SYBRGreen , ROX
FYT104-400P	Yeastern Biotech	400 Preps 1.25 ml x 4	Ask for price

Eztime Real - time PCRPremix 2x,Taqman, ROX
FYT105-400P	Yeastern Biotech	400 Preps 1.25 ml x 4	Ask for price

Eztime Real - time PCRPremix 2x,Taqman, ROX
FYT106-100P	Yeastern Biotech	100 Preps 1.25 ml	Ask for price

Green Dye One Step qRT-PCR Master Mix For Quantitative Real Time PCR With ROX Dye
MB1004-100Reactions	BosterBio	100 Reactions	EUR 392.4

hsa-let-7a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097603	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097604	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097605	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7d Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097606	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7e Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097607	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7f Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097608	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7g Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097609	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7i Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097610	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-let-7f Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097611	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-1 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097612	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-7 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097613	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-9 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097614	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-9* Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097615	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-10a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097616	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-10b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097617	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-10a* Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097618	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-15a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097619	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-15b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097620	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-16 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097622	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-18a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097625	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-18b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097626	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-19a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097627	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-19b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097628	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-20a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097629	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-20b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097630	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-21 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097631	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-22 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097632	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-23a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097633	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-23b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097634	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-25 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097636	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-26a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097637	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-26b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097638	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-27a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097639	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-27b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097640	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-29a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097642	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-29b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097643	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-29c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097644	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-30a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097645	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-30b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097647	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-30c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097648	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-30d Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097650	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-30e Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097651	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-31 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097652	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-32 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097653	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-33a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097654	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-34a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097657	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-34b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097659	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-92a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097661	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-92b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097662	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-93 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097663	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-95 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097664	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-96 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097665	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-98 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097666	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-99a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097667	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-99b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097669	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-100 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097671	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-101 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097673	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-103 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097675	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-105 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097676	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-106a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097677	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-106b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097678	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-107 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097679	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-124 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097680	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-125a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097681	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-127 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097686	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-129 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097689	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-130a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097690	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-130b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097691	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-132 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097692	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-133a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097693	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-133b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097694	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-134 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097695	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-135b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097696	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-137 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097699	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-138 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097700	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-139 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097701	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-140 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097702	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-141 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097703	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-143 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097706	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-145 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097708	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-146a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097709	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-149 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097711	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-150 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097712	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-151 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097714	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-152 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097715	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-153 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097716	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-154 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097717	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-181a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097719	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-181b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097720	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-181c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097721	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-181d Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097722	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-182 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097723	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-183 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097724	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-184 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097725	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-185 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097726	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-190a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097728	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-190b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097729	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-192 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097731	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-193a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097732	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-193b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097733	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-194 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097734	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-195 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097735	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-197 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097738	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-198 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097739	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-199a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097740	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-199b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097741	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-200a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097742	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-200b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097743	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-202 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097745	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-203 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097746	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-204 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097747	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-205 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097748	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-206 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097749	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-208a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097750	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-208b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097751	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-211 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097753	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

hsa-mir-212 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit
20-abx097754	Abbexa	EUR 878.40 EUR 1245.60 EUR 627.60	100 rxns 200 rxns 50 rxns

Circulating Vitamin D Ranges and DNA Restore Capability in 4 Molecular Subtypes of Girls with Breast Most cancers

Vitamin D regulates estrogen synthesis amongst completely different mechanisms involved in breast most cancers (BC) progress; nonetheless, no proof has been found regarding its relationship with DNA restore functionality (DRC). Subsequently, the goal of this analysis was to elucidate whether or not or not DRC ranges are linked with plasma 25(OH)D ranges.

• BC circumstances and controls have been chosen from our BC cohort. DRC ranges have been assessed in lymphocytes by the host-cell reactivation assay. 25(OH)D ranges have been measured using the UniCel DxI 600 Entry Immunoassay System. BC circumstances (n = 91) confirmed bigger 25(OH)D ranges than the controls (n = 92) (p = 0.001).

• When stratifying BC circumstances and controls into excessive and low DRC lessons, BC circumstances with low DRC (n = 74) had one of the best 25(OH)D ranges (p = 0.0001).

• A constructive correlation between 25(OH)D and DRC ranges was found for the controls (r = 0.215, p = 0.043) whereas a harmful correlation was found for BC circumstances (r = -0.236, p = 0.026). Essential variations in 25(OH)D ranges have been seen when stratifying by molecular subtypes (p = 0.0025).

• Our analysis provides proof of a hyperlink between 25(OH)D and DRC in BC along with a top level view of to how 25(OH)D ranges fluctuate all through subtypes. The constructive correlation seen inside the administration group signifies that 25(OH)D contributes otherwise to DRC ranges as quickly because the malignancy is developed.

Intercourse-specific associations with DNA methylation in lung tissue present smoking interactions

Cigarette smoking impacts DNA methylation, nevertheless the investigation of sex-specific choices of lung tissue DNA methylation in individuals who smoke has been restricted. Women appear additional vulnerable to cigarette smoke, and generally develop additional excessive lung sickness at an earlier age with a lot much less smoke publicity.

We aimed to analyse whether or not or not there are intercourse variations in DNA methylation in lung tissue and whether or not or not these DNA methylation marks work along with smoking. We collected lung tissue samples from former individuals who smoke who underwent lung tissue resection. 100 thirty samples from white subjects have been included for this analysis. Regression fashions for intercourse as a predictor of methylation have been adjusted for age, presence of COPD, smoking variables and technical batch variables revealed 710 associated web sites.

294 web sites demonstrated sturdy sex-specific methylation associations in foetal lung tissue. Pathway analysis acknowledged 6 nominally very important pathways along with the mitophagy pathway. Three CpG web sites demonstrated a urged interaction between intercourse and pack-years of smoking: GPR132, ANKRD44 and C19orf60.

All of them have been nominally very important in every male- and female-specific fashions, and the affect estimates have been in reverse directions for feminine and male; GPR132 demonstrated very important affiliation between DNA methylation and gene expression in lung tissue (P< 0.05). Intercourse-specific associations with DNA methylation in lung tissue are wide-spread and can reveal genes and pathways associated to intercourse variations for lung damaging outcomes of cigarette smoking.

Environment friendly detection of eukaryotic calcium-sensing receptor (CaSR) by polyclonal antibody towards prokaryotic expressed truncated CaSR

 The calcium-sensing receptor (CaSR), which is best identified for its motion as regulating calcium homeostasis, can bind numerous ligands. To facilitate analysis on CaSR and perceive the receptor’s perform additional, an in silico designed truncated protein was developed. The ensuing protein folding indicated that 99% of predicted three dimensional (3D) construction residues are positioned in favored and allowed Ramachandran plots. Nevertheless, it was discovered that such protein doesn’t fold correctly when expressed in prokaryotic host cells.

Thioredoxin (Trx) tag was conjugated to extend the ultimate protein’s solubility, which might assist get hold of the soluble antigen with higher immunogenic properties. The truncated recombinant proteins have been expressed and purified in two varieties (Trx-CaSR: RR19 and CaSR: RRJ19). The polyclonal antibody was induced by the rabbit immunization with the type of RR19. Western blot on mouse kidney lysates evidenced the right immune recognition of the receptor by the produced antibody.

The specificity and sensitivity of antibodies have been additionally assayed by immunohistofluorescence. These experiments affirmed antibody’s capacity to point the receptor on the cell floor in native type and the opportunity of making use of such antibodies in additional mobile and tissue assays.

GPCR RDC1 Antibody
49041-100ul	SAB	100ul	EUR 399.6

GPCR RDC1 Antibody
49041-50ul	SAB	50ul	EUR 286.8

GPCR GPR65 Antibody
DF13937	Affbiotech	100ul	EUR 420

GPCR TGR5 Antibody
DF14067	Affbiotech	100ul	EUR 420

anti-GPCR GPR146
YF-PA21926	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Anti-GPCR GPR146

anti-GPCR MRGX2
YF-PA22009	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Anti-GPCR MRGX2

anti-GPCR LOC51210
YF-PA22204	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210
YF-PA22205	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210
YF-PA22206	Abfrontier	100 ul	EUR 483.6
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR LOC51210
YF-PA22207	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR 2037
YF-PA22241	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Anti-GPCR 2037

anti-GPCR GPR110
YF-PA22867	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR110
YF-PA22868	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR3
YF-PA23809	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR GPR3
YF-PA12103	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR GPR34
YF-PA12105	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR GPR34

anti-GPCR C5L2
YF-PA18412	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR C5L2

anti-GPCR SALPR
YF-PA18968	Abfrontier	50 ul	EUR 435.6
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR GPRC5D
YF-PA19735	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR GPR62
YF-PA26842	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR GPR62

anti-GPCR LOC51210
YF-PA26875	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR HM74
YF-PA15914	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to GPCR HM74

anti-GPCR SALPR
YF-PA26165	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR EX33
YF-PA26233	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR EX33

anti-GPCR GPRC5D
YF-PA26334	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR LGR7
YF-PA26522	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR LGR7

anti-GPCR LGR6
YF-PA26523	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR LGR6

anti-GPCR TAS1R1
YF-PA26658	Abfrontier	50 ul	EUR 400.8
Description: Mouse polyclonal to GPCR TAS1R1

Anti-D-GPCR Antibody
A12058	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal Antibody for D-GPCR Antibody (OR51E1) detection.tested for WB in Human.

D-GPCR Polyclonal Antibody
ABP51168-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody
ABP51168-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody
ABP51168-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

GPCR GPR86 Conjugated Antibody
C48382	SAB	100ul	EUR 476.4

GPCR RDC1 Conjugated Antibody
C49041	SAB	100ul	EUR 476.4

D-GPCR Polyclonal Antibody
ES2167-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

D-GPCR Polyclonal Antibody
ES2167-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Porcine GPCR ELISA Kit
EPG0026	Abclonal	96Tests	EUR 625.2

Rabbit GPCR ELISA Kit
ERTG0026	Abclonal	96Tests	EUR 625.2

Rat GPCR ELISA Kit
ERG0026	Abclonal	96Tests	EUR 625.2

Mouse GPCR ELISA Kit
EMG0026	Abclonal	96Tests	EUR 625.2

Monkey GPCR ELISA Kit
EMKG0026	Abclonal	96Tests	EUR 625.2

Human GPCR ELISA Kit
EHG0026	Abclonal	96Tests	EUR 625.2

Goat GPCR ELISA Kit
EGTG0026	Abclonal	96Tests	EUR 625.2

Bovine GPCR ELISA Kit
EBG0026	Abclonal	96Tests	EUR 625.2

Canine GPCR ELISA Kit
ECG0026	Abclonal	96Tests	EUR 625.2

Chicken GPCR ELISA Kit
ECKG0026	Abclonal	96Tests	EUR 625.2

DiscoveryProbe? GPCR Compound Library
L1025-.1	ApexBio	100 uL/well(10 mM solution)	EUR 5683.2

DiscoveryProbe? GPCR Compound Library
L1025-.25	ApexBio	250 uL/well(10 mM solution)	EUR 10221.6

DiscoveryProbe? GPCR Compound Library
L1025-5	ApexBio	5 mg/well	EUR 13284

Sheep GPCR ELISA Kit
ESG0026	Abclonal	96Tests	EUR 625.2

Anti-D-GPCR antibody
STJ92705	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to D-GPCR.

Anti-GPCR GPR40 Antibody
STJ501005	St John's Laboratory	100 µg	EUR 571.2

Anti-GPCR GPR3 Antibody
STJ501253	St John's Laboratory	100 µg	EUR 571.2

Anti-GPCR SALPR (1F10)
YF-MA18467	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR SALPR

Anti-GPCR EX33 (5C3)
YF-MA18601	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (5B7)
YF-MA18602	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (1D9)
YF-MA18603	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR GPR48 (8F6)
YF-MA18780	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR GPR48

Anti-GPCR GPRC5D (6D9)
YF-MA18788	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR GPRC5D

Anti-GPCR LOC51210 (6D7)
YF-MA19845	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR LOC51210

Anti-GPCR LGR7 (3E3)
YF-MA11622	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to GPCR LGR7

Anti-GPCR GPR40/FFAR1 Antibody
A01349-2	BosterBio	100ug/vial	EUR 352.8

Anti-GPCR LGR8/RXFP2 Antibody
A04848-1	BosterBio	100ug/vial	EUR 400.8

Anti-LGR6/Gpcr Lgr6 Antibody
A05990	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal LGR6/Gpcr Lgr6 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GPCR GPR7/NPBWR1 Antibody
A08247-1	BosterBio	100ug/vial	EUR 352.8

Anti-GPR151/Gpcr 2037 Antibody
A14582	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-GPR151/Gpcr 2037 Antibody
A30814	BosterBio	100ul	EUR 476.4
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in IF, WB and tested in Mouse, Rat.

Guinea Pig GPCR ELISA Kit
EGG0026	Abclonal	96Tests	EUR 625.2

Anserini GPCR-APJ ELISA Kit
EAG0026	Abclonal	96Tests	EUR 625.2

Anti-GPCR GPR40 Antibody BIOTIN
STJ501006	St John's Laboratory	100 µg	EUR 703.2

Anti-GPCR GPR40 Antibody FITC
STJ501007	St John's Laboratory	100 µg	EUR 703.2

Anti-GPCR GPR3 Antibody BIOTIN
STJ501254	St John's Laboratory	100 µg	EUR 703.2

Anti-GPCR GPR3 Antibody FITC
STJ501255	St John's Laboratory	100 µg	EUR 703.2

anti-5-oxo-ETE GPCR
YF-PA22585	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to 5-oxo-ETE GPCR

Phosphatase Orphan-2 (Recombinant)
20-abx073747	Abbexa	EUR 393.60 EUR 7676.40 EUR 276.00	10 ug 1 mg 2 µg

Phosphatase Orphan-1 (Recombinant)
20-abx073910	Abbexa	EUR 393.60 EUR 8829.60 EUR 276.00	10 ug 1 mg 2 µg

DiscoveryProbe? GPCR/G protein-related Compounds Panel
L1009-5	ApexBio	5 mg/well	EUR 7242
Description: A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc.

Recombinant Human RAR-Related Orphan Receptor C
7-06163	CHI Scientific	5µg	Ask for price

Recombinant Human RAR-Related Orphan Receptor C
7-06164	CHI Scientific	20µg	Ask for price

Recombinant Human RAR-Related Orphan Receptor C
7-06165	CHI Scientific	1mg	Ask for price

RAR Related Orphan Receptor Alpha (RORa) Antibody
20-abx103508	Abbexa	EUR 376.80 EUR 159.60 EUR 978.00 EUR 510.00 EUR 326.40	100 ug 10 ug 1 mg 200 ug 50 ug

RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx103509	Abbexa	EUR 510.00 EUR 159.60 EUR 1446.00 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx005288	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx119555	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx130085	Abbexa	EUR 543.60 EUR 159.60 EUR 1562.40 EUR 744.00 EUR 410.40	100 ug 10 ug 1 mg 200 ug 50 ug

Rar-Related Orphan Receptor A (RORA) Antibody
20-abx115045	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Rar-Related Orphan Receptor B (RORB) Antibody
20-abx115046	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Rar-Related Orphan Receptor C (RORC) Antibody
20-abx115047	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Intermediate Filament Family Orphan 1 (IFFO1) Antibody
20-abx113262	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

RAR Related Orphan Receptor Gamma (RORG) Antibody
20-abx013514	Abbexa	EUR 376.80 EUR 117.60 EUR 477.60 EUR 594.00	100 ug 10 ug 200 ug 300 µg

RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-400ul	Abbexa	400 ul	EUR 627.6

RAR Related Orphan Receptor Beta (RORB) Antibody
abx027769-80l	Abbexa	80 µl	EUR 343.2

RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-400ul	Abbexa	400 ul	EUR 627.6

RAR Related Orphan Receptor Alpha (RORA) Antibody
abx025951-80l	Abbexa	80 µl	EUR 343.2

Intermediate Filament Family Orphan 1 (IFFO1) Antibody
abx037159-100ug	Abbexa	100 ug	EUR 469.2

RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx178212	Abbexa	EUR 1562.40 EUR 744.00	1 mg 200 ug

RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx338779	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

RAR Related Orphan Receptor Gamma (RORG) Protein
20-abx261968	Abbexa	EUR 5388.00 EUR 393.60 EUR 276.00	1 mg 20 ug 5 ug

RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx325108	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Intermediate Filament Family Orphan 1 (IFFO1) Antibody
abx234132-100ug	Abbexa	100 ug	EUR 577.2

RAR Related Orphan Receptor Alpha (RORA) Antibody
20-abx211380	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214131	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

RAR Related Orphan Receptor Beta (RORB) Antibody
20-abx214132	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Neuron Derived Orphan Receptor 1 (NOR1) Antibody
20-abx173779	Abbexa	EUR 1095.60 EUR 560.40	1 mg 200 ug

RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx174332	Abbexa	EUR 1028.40 EUR 526.80	1 mg 200 ug

RAR Related Orphan Receptor Gamma (RORg) Antibody
20-abx174333	Abbexa	EUR 1095.60 EUR 560.40	1 mg 200 ug

RAR Related Orphan Receptor Alpha (RORA) Antibody
abx237387-100ug	Abbexa	100 ug	EUR 610.8

RAR Related Orphan Receptor Beta (RORB) Antibody
abx237388-100ug	Abbexa	100 ug	EUR 610.8

PHOSPHO2 Phosphatase Orphan-2 Human Recombinant Protein
PROTQ8TCD6	BosterBio	Regular: 10ug	EUR 380.4
Description: PHOSPHO2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (1-241) and having a molecular mass of 30.3kDa.;PHOSPHO2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PHOSPHO1 Phosphatase Orphan-1 Human Recombinant Protein
PROTQ8TCT1	BosterBio	Regular: 10ug	EUR 380.4
Description: Human Phospho1 Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 295 amino acids and having a molecular mass of 31.3 kDa. The Human Phospho1 is fused to a 14 aa His tag at N-Terminus. Human Phosphocholine Phosphatase is purified by proprietary chromatographic techniques.

Recombinant Neuron Derived Orphan Receptor 1 (NOR1)
4-RPC675Ra01	Cloud-Clone	EUR 614.59 EUR 288.00 EUR 1974.72 EUR 738.24 EUR 1356.48 EUR 487.20 EUR 4756.80	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Neuron Derived Orphan Receptor 1 expressed in: E.coli

Recombinant RAR Related Orphan Receptor Alpha (RORa)
4-RPD947Hu01	Cloud-Clone	EUR 580.19 EUR 278.40 EUR 1845.70 EUR 695.23 EUR 1270.46 EUR 463.20 EUR 4434.24	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human RAR Related Orphan Receptor Alpha expressed in: E.coli

Recombinant RAR Related Orphan Receptor Gamma (RORg)
4-RPD949Hu01	Cloud-Clone	EUR 586.63 EUR 280.80 EUR 1869.89 EUR 703.30 EUR 1286.59 EUR 468.00 EUR 4494.72	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human RAR Related Orphan Receptor Gamma expressed in: E.coli

Cell Meter™ Beta-Arrestin Translocation GPCR Signaling Kit
36390	AAT Bioquest	100 Tests	EUR 781

Cell Meter™ Beta-Arrestin Translocation GPCR Signaling Kit
36391	AAT Bioquest	200 Tests	EUR 989

Rat Neuron Derived Orphan Receptor 1 (NOR1) Protein
20-abx167704	Abbexa	EUR 861.60 EUR 343.20 EUR 2665.20 EUR 1028.40 EUR 610.80	100 ug 10 ug 1 mg 200 ug 50 ug

Human RAR Related Orphan Receptor Alpha (RORa) Protein
20-abx068824	Abbexa	EUR 811.20 EUR 326.40 EUR 2481.60 EUR 961.20 EUR 577.20	100 ug 10 ug 1 mg 200 ug 50 ug

Human RAR Related Orphan Receptor Gamma (RORg) Protein
20-abx068825	Abbexa	EUR 828.00 EUR 343.20 EUR 2515.20 EUR 978.00 EUR 594.00	100 ug 10 ug 1 mg 200 ug 50 ug

Receptor Tyrosine Kinase-Like Orphan Receptor 1 Antibody
20-abx115089	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

RAR Related Orphan Receptor Alpha (RORA) Antibody (HRP)
20-abx336856	Abbexa	EUR 493.20